Preformulation and Stabilization of Pharmaceuticals
Industrial Short Course
May 3-7, 2010
Pyle Center
Madison, WI
On Campus Short Courses for the Pharmaceutical Industry
Registration
The registration is $1395.00 and Early bird registration ($1145) are offered to individuals registering prior to April 16, 2010.
Your registration options are as follows:
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Register Online. Login in using your user account. If you don't have a user account creating one is free & easy. |
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Download the registration form, complete & mail to: Pharmacy Short Courses |
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By phone at 608.262.3132 or 608.262.3130 or toll-free at 877-947-4255 using a credit card for payment. |
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Download the registration form, complete & fax to 608.262.2431 using a credit card for payment. |
Goals & Objectives
The objective of this short course is to provide the formulation and analytical scientist with an understanding of preformulation science, physical and chemical characterization, and stability of solid- and liquid-dosage forms. Upon completion of this course, the learner should be able to:
- determine the biopharmaceutical and physical chemical properties of new chemical entities in order to develop dosage forms;
- interpret kinetic data;
- have a working knowledge of common degradation mechanisms;
- propose approaches to overcome chemical stability challenges in dosage form development.
This course includes computer laboratory sessions to interpret preformulation and stability data.
Special Offer for Academic Institutions
Extension Services in Pharmacy at the University of Wisconsin School of Pharmacy has instituted a new policy for industrial professional development programs to encourage greater participation by faculty, graduate students and post doctoral students at academic institutions. Programs will be offered at a significantly reduced price, based on space availability. For information about any specific course please contact Dr. James E. De Muth by email.
Short Course Program General Information
Purpose
The primary objective in all short courses is to upgrade the knowledge of pharmaceutical personnel, who can then be of greater value to their respective firms. Students will work closely with one or more faculty members to allow for optimum dialogue and discussion. We also have modified some of the courses based on evaluations and suggestions from previous participants. As with all our programs, these are designed to be practical and applicable to participants' work environments. To allow for maximum faculty-student interaction, the enrollment will be limited and available to learners on a first-come basis.
Last year, over 90% agreed or strongly agreed that the program was a valuable learning experience and over 88% indicated that they would recommend the course to a colleague.
Location
Courses are presented on the University of Wisconsin-Madison Campus. Springtime in Madison and the beauty of the on-campus location provide a relaxing atmosphere for learning. Evenings can be used to explore the University and the city named by Money magazine as the "best place to live in America" in 1996. For more information about Madison, WI visit www.visitmadison.com
Accommodations
Housing information will be sent to individuals when they receive their registration confirmation. Several hotels are within a short walking distance from the conference facility. The approximate cost per night is $100.
Ending/Starting Times
Classes begin at 8:30am each morning and end approximately 4:30. Unless otherwise indicated in the course description, programs traditionally end at approximately 11:00 to 11:30 AM on the last day of the class. This allows participants to make reservations for return flights the same day.
Enrollment & Fees
Unless otherwise indicated, enrollment will be limited to 30 individuals per short course. The registration fee of $1395.00 includes instructional costs, course materials, and coffee breaks, and lunches. Cancellations after April 16 are non-refundable. Cancellations prior to April 16 are subject to a $75 administration fee. In the event that an accepted applicant cannot attend, a substitute may be sent by the same company. Early bird discounts ($1145) are offered to individuals registering prior to April 16, 2010. In 2007, seven of the nine short courses filled before the early registration deadline. You are encouraged to register early to avoid not being able to be included in the program.
Contents
- Solution physical chemical properties, including partition coefficient, ionic equilibria, and solubility
- Reaction rates and rate equations; zero-, first-, and second-order reactions; graphical interpretation of data; determination of rate constants; half-life and shelf-life
- Kinetic theory: collision theory; activation energy; and Arrhenius equation
- Stability of solution dosage forms: hydrolysis; pH effects; buffer catalysis; co-solvent effects; oxidation
- Case studies on stabilization of drug by complexation and partitioning
- Solid-state physical chemical properties, including particle size, dissolution, surface area, compactibility
- Biopharmaceutics: Effects of physical chemical properties on bioavailability
- Solid-state stability of crystalline systems
- Polymorphism and crystal-form screening
- Physical chemical properties of amorphous solids, including glass transition temperatures and molecular mobility
- Effects of moisture on pharmaceutical solids
- Drug-excipient interactions
- Processing effects on the stability of solid dosage forms
- Analytical and Qualification Strategies for degradation products
Instructors
Raymond D. Skwierczynski, Ph.D.
Director, Analytical Development and Formulation Science
Millennium Pharmaceuticals
Cambridge, MA
Scott W. Smith, Ph.D.
Director of Physical Chemistry
Allergan
Irvine, CA
For More Information
James E. De Muth, Ph.D., Conference Director
Extension Services in Pharmacy
777 Highland Avenue
Madison, WI 53705
(608) 262-3130
FAX (608) 262-2431
Send Email
