11th Annual Land O’Lakes Bioanalytical Conference
A New Decade of Bioanalysis of Large and Small Molecules
July 19-23, 2010
Devil’s Head Resort
Merrimac, WI
Developed & Conducted by Extension Services in Pharmacy, School of Pharmacy, University of Wisconsin-Madison.
Menu
Registration
Goals & Objectives
Special Offer for Academic Institutions
Conference Travel Information
Program Outline
Conference Planning Committee
Social Activities
More Information
Special Offer for Academic Institutions
Extension Services in Pharmacy at the University of Wisconsin School of Pharmacy has instituted a new policy for industrial professional development programs to encourage greater participation by faculty, graduate students and post doctoral students at academic institutions. Programs will be offered at a significantly reduced price, based on space availability. For information about any specific course please contact Dr. James E. De Muth by email.
Global Conference Goals & Objectives
The purpose of this four-day conference is to provide an educational forum to discuss issues and applications associated with the analysis of xenobiotics, their metabolites and endogenous biomarkers in biological matrices. The conference is designed to include and encourage an open exchange of scientific and methodological applications for bioanalysis. To increase the interactive nature of the conference, the program will be a mixture of lecture, discussion groups and workshops. Goals associated with this conference include:
- To provide a better understanding of the bioanalysis of large and small molecule xenobiotics, biomarkers and immunogenicity in biological matrices;
- To evaluate new technology and share experiences;
- To gain insight into problems and issues encountered during the drug discovery process and the interface between drug discovery and development;
- To discuss current global regulatory issues affecting bioanalysis;
- To identify processes for improving the identification and quantification of successful drug candidates and their measurement, including in vitro/in vivo implications;
- To discuss analytical issues relating to drug metabolism and pharmacokinetics and their applicability in drug development activity;
- To discuss issues associated with information management, data handling and automation in bioanalytical laboratories;
- To gain insight into various perspectives on the drug development process, including industry, academia and regulatory agencies; and
- To evaluate the harmonization of methods validation, quality control and set standards for drug metabolite identification in studies involving bioanalysis.
Evaluation results from 2009 Conference
Slides generated from Workshop dealing with daily lab problems
2009 Conference Travel Information
Location & Travel
The conference will be presented at Devil's Head Resort in Merrimac, Wisconsin. Merrimac is approximately 40 minutes from Madison. For those registrants flying into Madison, bus transportation will be available to and from Devil's Head Resort.
Shuttle Bus Service to and from the Dane County Regional Airport
Monday 1:30 and 4:30 PM |
Friday 10:45 AM |
Sponsored by:
|
 |
2010 Conference fees
Registration Fee |
$1250.00 |
Lodging & Meals: Single Accommodations |
$625.00 |
Total Amount |
$1,875.00 |
If Payment received prior to June 21, 2010 |
-$150.00 |
EARLY REGISTRATION |
$1,725.00 |
NOTE: All accommodations at Devil's Head for conference registrants will be processed through Extension Services in Pharmacy. Fees are based on a single accommodation. Additional fees will be assessed for both lodging in the event more than one person occupies a room.
Enrollment Deadlines/Limits
A check in the total amount payable to UNIVERSITY OF WISCONSIN should accompany your application to ensure that space will be held for you. Credit card payment is also acceptable. Total payment will be returned /refunded if space is not available.
In the event your registration is confirmed and at a later date you are unable to personally attend, a refund (less a $50 administrative fee) will be provided prior to June 21; after June 21, no refunds will be made. You may fax your registration (608) 262-2431 with payment to follow no later than June 21. After June 21, space will not be held without receipt of payment.
Conference Support for 2010
Speical thanks for unrestricted educational grant to help support this conference from
Enthalpy Analytical, Inc. |  |
PPD, Inc. |  |
Covance Laboratories |  |
York Bioanalytical Solutions |  |
2009 Program Outline (2010 Program is currently being developed)
Monday, July 13 |
|||||
6:00pm |
Opening Reception
|
||||
7:00pm |
Dinner
|
||||
Tuesday, July 14 |
First Plenary Session: New Technologies with Analytical Applications
|
||||
8:00am |
Welcome and Overview |
||||
8:15am |
Microfluidics and Immunoassay Applications for Large Molecules
|
||||
9:05am |
Biomarker Large Molecule Conversion to LC-MS/MS
|
||||
9:55am |
Break |
||||
10:20am |
Ion Transmission to Improve Sensitivity of MS
|
||||
11:10am | Detecting, Identifying and Quantifying Metabolites from First-in-Human Studies: Role of Orbitrap MS
| ||||
|
12:00pm |
Lunch |
||||
1:00pm | Afternoon Session –Identifying Metabolites Using Alternative Approaches and Complying with MIST Guidance
| ||||
|
1:00 |
Obtaining Exposures of Metabolites in Preclinical Species Through Plasma Pooling and Quantitative NMR
|
||||
|
1:25 |
Bioanalytical Techniques with a TWIST to support MIST
|
||||
|
1:50 |
Analytical Strategies for Post-MIST Clarity
|
||||
2:15 | Panel Discussion
| ||||
|
2:45pm |
Boat tour of the Wisconsin Dells
|
||||
|
6:30pm |
Dinner |
||||
|
|
Evening Session
|
||||
|
8:00pm |
Transfer, Development and Validation of Cell-based Neutralizing Antibodies (NAb) Assays
|
||||
|
9:00pm |
Dessert Reception
|
||||
|
Wednesday, July 15 |
Second Plenary Session –Bioanalytical Sample Preparation
|
||||
|
8:00am |
Comparison of Technologies for Phospholipid Removal
|
||||
8:50am |
Derivatization
|
||||
9:40am |
Break |
||||
10:20am |
The Use of Dried Blood Spot Samples for the Quantitative Bioanalysis of Drugs in PreClinical and Clinical Studies
|
||||
|
11:10am |
Mass Spectrometry-based Enzyme Assays for High Throughput, Label-free Screening
|
||||
12:00pm |
Lunch |
||||
1:00pm |
Two Parallel Short Courses (two hours each)
|
||||
|
5:00pm |
Poster Session
|
||||
|
6:30pm |
Dinner |
||||
|
8:00pm |
Evening Round Table Discussions
|
||||
|
Thursday, July 16 |
Third Plenary Session – Chromatographic Applications to Bioassays
|
||||
|
8:00am |
Liquid Chromatography and Affinity-Based Separations in Bioanalysis: An Overview
|
||||
|
9:00am |
Use of Ion Exchange Chromatography in Routine Small Molecule Analysis
|
||||
|
9:40am |
Break |
||||
|
10:20am |
Normal Phase and Reverse Phase Methodologies in Support of Lipidomic Assays
|
||||
|
11:10am |
Fast and Two Dimensional Liquid Chromatography
|
||||
|
12:00pm |
Lunch |
||||
|
|
Afternoon Workshop |
||||
|
1:00pm |
Open Forum: Dealing with Daily Problems
|
||||
|
2:45pm |
Tour - Circus World Museum (http://circusworld.wisconsinhistory.org)
|
||||
|
6:00pm |
Dinner |
||||
|
|
Evening Session - Analytical Investigators’ Forum
|
||||
7:30pm |
Applications of UPLC-MS/MS in Bioanalysis
|
||||
8:00pm |
Improving Digestion Efficiency for MS/MS Quantitation for Large Proteins
|
||||
8:30 |
Ligand Binding Assay Specificity: Addressing Issues with Combination Therapies
|
||||
9:00pm |
Wisconsin Cheese Boxes
|
||||
Friday, July 17 |
Fourth Plenary Session – Biosimilar Products: Comparison of Regulatory Standards
|
||||
8:00am |
An Overview of Biosimilar Products
|
||||
8:45am |
US Perspective on Biosimilar Products
|
||||
9:25am |
European Perspective on Biosimilar Products
|
||||
10:10am |
Panel Discussion
|
||||
10:30am |
Adjournment |
||||
|
2009 Conference Planning Committee
Lakshmi Amaravadi, Ph.D., BiogenIdec, Cambridge, MA
Mark Arnold, Ph.D., Bristol-Myers Squibb Company, New Brunswick, NJ
Brian P Booth, Ph.D., Food and Drug Administration/CDER, Rockville, MD
Chad Briscoe, MDS Pharma Services, Lincoln, NE
Janice Bush, Pfizer Global Research and Development, New London, CT
Min S. Chang, Ph.D., Biogen Idec, San Diego, CA
Robert Clement, Ph.D., Schering-Plough Research Institute, Lafayette, NJ
Christopher A. Evans, Ph.D.., GlaxoSmithKline, King of Prussia, PA
James E. De Muth, Ph.D., University of Wisconsin, Madison, WI, Conference Director
Eric N. Fluhler, Ph.D., Wyeth Research, Pearl River, NY
Russell P. Grant, Ph.D., LabCorp, Burlington, NC
Michael J. Hayes, Ph.D., Novartis Pharmaceuticals Corporation, East Hanover, NJ, Conference Chair
Stacy Ho, Ph.D., Genzyme Corporation, Waltham, MA
Qin C. Ji, Ph.D., Bristol-Myers Squibb Company, Princeton, NJ
Tom Huggins, Ph.D., Procter and Gamble, Mason, OH
Douglas J. Turk, Ph.D., NoAb BioDiscoveries Inc., Mississauga, Ontario, Canada
Danlin Wu, Ph.D., Roche Palo Alto, Palo Alto, CA
Social Activities
In addition to the educational benefits of this program, the conference is designed to provide registrants with a relaxing environment to meet and share ideas with colleagues with similar interests and network for future collaborative effort. To this end, Devil's Head Resort offers a variety of activities including tennis, indoor and outdoor swimming pools, mountain bikes, nature trails and one of the finest golf courses in Wisconsin. Golf, at a significantly reduced rate, is available to all registrants during Tuesday and Wednesday afternoons of the conference.
Click here to view photos from 2007
For More Information
James E. De Muth, Ph.D., Conference Director
Extension Services in Pharmacy
777 Highland Avenue
Madison, WI 53705
(608) 262-3130
FAX (608) 262-2431
