QbD for Solid Dosage Forms:
Designing Tablet Formulations Based on API Physical Properties
Industrial Short Course
November 2, 2009
Doubletree Somerset Hotel & Executive Meeting Center
200 Atrium Drive
Somerset, NJ
Short Courses for the Pharmaceutical Industry
Registration
Your registration options are as follows:
The registration is $950.00 and Early bird discounts ($750) are offered to individuals registering prior to October 18, 2009.
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Register Online. Login in using your user account. If you don't have a user account creating one is free & easy. |
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Download the registration form, complete & mail to: Pharmacy Short Courses |
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By phone at 608.262.3130 or toll-free at 877-947-4255 using a credit card for payment. |
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Download the registration form, complete & fax to 608.262.2431 using a credit card for payment. |
Goals & Objectives
Goals and Objectives
The objective of this University of Wisconsin-Madison professional development course is to provide the participant with an understanding of how fundamental physical properties of APIs impact the design and manufacture of tablet dosage forms. Upon completion of the course the learner should be able to:
- describe the basic physical properties of powders that are of importance for tablet manufacturing,
- explain how powder physical properties control flow, segregation and compaction performance,
- select excipients based on the physical properties of the API,
- understand the interdependence of the tensile strength, compression stress and solid fraction of the final product; and
- select tablet manufacturing equipment and conditions to maximize productivity and quality.
An emphasis will be placed on practical approaches that can be used for rational tablet design and development in accordance with Quality-by-Design principles. The class will include opportunities for problem solving in small groups and as individuals.
Short Course Program General Information
Who should attend
Scientists and engineers who are interested in applying materials science and engineering principles to the development of tablet dosage formulations. Additional individuals who may benefit include those involved in regulatory, quality control, analytical, process development, and quality assurance roles.
Location
Doubletree Somerset Hotel & Executive Meeting Center
200 Atrium Drive
Somerset, NJ 08873
(732) 469-2600
The day begins (8:00am) with a continental breakfast and includes lunch and break service throughout the day. All classes will begin at 8:30am and end at approximately 5:00pm.
Accommodations
Blocks of hotel rooms have been reserved at the DoubleTree Hotel at the rate of $99.00 per night. Reservations should be made directly with the hotel at (800) 222-TREE and request University of Wisconsin Short Courses block. To guarantee this special room rate, reservations must be made by October 16.
Enrollment & Fees
One-day Short Course (any of the six other programs) $ 950
Payment received prior to October 18, 2009: $ 750
Topics
1) principles of powder flow, segregation and compaction
2) material sparing characterization of API properties
3) rational selection of excipients
4) concepts of tensile strength, compression stress and solid fraction
5) importance of particle size and viscoelasticity (“speed dependence”)
6) tablet press design and principles of operation (single station and rotary)
7) tablet shape effects and tooling design
Special Offer for Academic Institutions
Extension Services in Pharmacy at the University of Wisconsin School of Pharmacy has instituted a new policy for industrial professional development programs to encourage greater participation by faculty, graduate students and post doctoral students at academic institutions. Programs will be offered at a significantly reduced price, based on space availability. For information about any specific course please contact Dr. James E. De Muth by email.
Instructors
Bruno C. Hancock, Ph.D.
Research Fellow, Global Research and Development, Pfizer Inc., Groton, CT
Dr. Hancock is responsible for the development of new predictive approaches for drug product design at Pfizer and has over 15 years experience working in the field of tablet formulation design. He has published over eighty peer reviewed papers and is a Fellow of the American Association of Pharmaceutical Scientists.
Matthew P. Mullarney, B.S., M.S.
Senior Scientist, Global Research and Development Pfizer Inc., Groton, CT
Matthew Mullarney has 10 years of experience at Pfizer in developing and implementing methods for studying the powder flow and compact mechanical properties of pharmaceutical powders using both experimental approaches and computational models. He is an active contributor to AAPS, USP, ASTM, and the Handbook of Pharmaceutical Excipients.
For More Information
James E. De Muth, Ph.D., Conference Director
Extension Services in Pharmacy
777 Highland Avenue
Madison, WI 53705
(608) 262-3130
FAX (608) 262-2431
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