An Introduction to Pharmacokinetics and Pharmacodynamics
Industrial Short Course
November 2-3, 2009
Doubletree Somerset Hotel & Executive Meeting Center
200 Atrium Drive
Somerset, NJ
Short Courses for the Pharmaceutical Industry
Registration
Your registration options are as follows:
The registration is $1450.00 and Early bird discounts ($1150) are offered to individuals registering prior to October 18, 2009.
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Register Online. Login in using your user account. If you don't have a user account creating one is free & easy. |
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Download the registration form, complete & mail to: Pharmacy Short Courses |
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By phone at 608.262.3130 or toll-free at 877-947-4255 using a credit card for payment. |
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Download the registration form, complete & fax to 608.262.2431 using a credit card for payment. |
Goals & Objectives
Goals and Objectives
The purpose of this two‑day University of Wisconsin-Madison professional development course is to provide the learner with a basic understanding of preclinical and clinical pharmacokinetics and pharmacodynamics of drugs. Practical examples based on actual experimental data will be used to illustrate concepts. Parameters used to describe a drug's pharmacokinetics and pharmacodynamics will be interpreted in terms of mammalian physiology. The course is presented from a conceptual physiological basis in which each concept is presented and then illustrated in the context of typically acquired experimental results. All pharmacokinetic terms are defined and illustrated along with providing the audience with a feel for the meaning and utility of the terminology. A particular emphasis is placed on describing the circumstances under which the standard pharmacokinetic models and associated assumptions breakdown and how to deal with these situations. Upon completion of this course, the learner should be able to:
- discuss the consequences of the first pass effect on drug availability;
- describe the rationale for treating the body as a one compartment model;
- have a conceptual understanding of half-life, clearance, volume of distribution, AUC and protein binding;
- define bioavailability and list the factors which affect bioavailability;
- understand the principles of species scaling and its strengths and weaknesses; and
- understand the inter-relationship between pharmacokinetics and pharmacodynamics.
Short Course Program General Information
Who should attend
This is an introductory course in pharmacokinetics and pharmacodynamics directed towards a general audience of scientists who are directly or indirectly involved in PK/PD studies. Typically individuals with backgrounds in medicinal chemistry, formulation, analytical chemistry, pharmacology, toxicology, biostatistics, biology or the clinical sciences have enrolled in this course.
Location
Doubletree Somerset Hotel & Executive Meeting Center
200 Atrium Drive
Somerset, NJ 08873
(732) 469-2600
Each day begins (8:00am) with a continental breakfast before the start of the course and includes lunch and break service throughout the day. Class will begin at 8:30am and end at approximately 5:00pm.
Accommodations
Blocks of hotel rooms have been reserved at the DoubleTree Hotel at the rate of $99.00 per night. Reservations should be made directly with the hotel at (800) 222-TREE and request University of Wisconsin Short Courses block. To guarantee this special room rate, reservations must be made by October 16.
Enrollment & Fees
Two-day PK/PD Short Course $1,450
Payment received prior to October 19, 2009: $1,150
Contents
1) Introduction: a discussion of the terminology used in pharmacokinetics
2) One compartment pharmacokinetic models
3) Plasma protein binding, volume of distribution
4) Clearance (renal and metabolic)
5) Drug interactions
6) Area under the concentration time profile and drug bioavailability
7) Individual variability (age, genetic, gender)
8) Distribution kinetics (two compartment pharmacokinetic model)
9) Metabolite kinetics
10) Dose dependent kinetics
11) Model independent kinetics
12) Pharmacological response
13) Pharmacokinetic and pharmacodynamic correlation models
14) Species scaling
Instructor
Ronald R. Burnette, Ph.D.
Associate Professor
School of Pharmacy, University of Wisconsin, Madison, WI
Dr. Burnette has taught more than 50 pharmacokinetics short courses for the pharmaceutical industry and they have always been well received and positively evaluated by participants. His teaching style and interaction with the learners makes this one of the most popular outreach courses at the University of Wisconsin-Madison.
For More Information
James E. De Muth, Ph.D., Conference Director
Extension Services in Pharmacy
777 Highland Avenue
Madison, WI 53705
(608) 262-3130
FAX (608) 262-2431
Send Email
Special Offer for Academic Institutions
Extension Services in Pharmacy at the University of Wisconsin School of Pharmacy has instituted a new policy for industrial professional development programs to encourage greater participation by faculty, graduate students and post doctoral students at academic institutions. Programs will be offered at a significantly reduced price, based on space availability. For information about any specific course please contact Dr. James E. De Muth by email.